google7fe7e6420122196f.html Preventive Medicine: Cancer Vaccine?

Friday, November 28, 2008

Cancer Vaccine?

vaccination is one of the preventive medicine's weapon

In medical industry, recently ,new vaccine for cervical cancer is approved by FDA. So, it's interesting to know about the CANCER VACCINE

The term cancer vaccine refers to a vaccine that either prevents infections with cancer-causing viruses, or treats existing cancer.

Some cancers, such as cervical cancer and some liver cancers, are caused by viruses, and traditional vaccines against those viruses, such as HPV vaccine and Hepatitis B vaccine, will prevent those cancers.

Gardasil: cervical cancer vaccine

GARDASIL is the only cervical cancer vaccine that helps protect against 4 types of human papillomavirus (HPV): 2 types that cause 70% of cervical cancer cases, and 2 more types that cause 90% of genital warts cases. GARDASIL is for girls and young women ages 9 to 26.Anyone who is allergic to the ingredients of GARDASIL, including those severely allergic to yeast, should not receive the vaccine. GARDASIL is not for women who are pregnant. GARDASIL does not treat cervical cancer or genital warts.GARDASIL may not fully protect everyone, and does not prevent all types of cervical cancer, so it’s important to continue routine cervical cancer screenings. GARDASIL will not protect against diseases caused by other HPV types or against diseases not caused by HPV.The side effects include pain, swelling, itching, bruising, and redness at the injection site, headache, fever, nausea, dizziness, vomiting, and fainting. GARDASIL is given as 3 injections over 6 months.


melanoma and renal cancer have failed to be faced by the cancer vaccine, possible explanations include:

1) disease stage being treated was too advanced: it is difficult to get the immune system to fight bulky tumor deposits, because tumors actively suppress the immune system using a variety of mechanisms (e.g. secretion of cytokines that inhibit immune activity). The most suitable stage for a cancer vaccine is likely to be early disease, when the tumor volume is low, 

2) escape loss variants (cancer vaccines that target just one tumor antigen are likely to be less effective. Tumors are highly heterogeneous and antigen expression differs markedly between tumors (even within deposits in the same patient). The most effective cancer vaccine is likely to raise an immune response against a broad range of tumor antigens to minimise the chance of the tumor being able to mutate and become resistant to the therapy.)

3) prior treatments (numerous clinical trials in the past have treated patients who have received numerous cycles of chemotherapy. Chemotherapy is often myelosuppressive and destroys the immune system. There is little point giving a cancer vaccine to a patient who is immune suppressed).

4) some tumors progress very rapidly and/or unpredictably, and they can literally outpace the immune system. It may take two to three months for an immune response to a vaccine to mature, but some cancers (e.g. advanced pancreatic) can produce marked clinical deterioration, or even death, within this timeframe.

5) many cancer vaccine clinical trials examine immune responses by patients as their primary goal. Correlations are then made, typically showing that the patients who made the strongest immune responses were the ones who lived the longest, and this is taken as evidence that the vaccine is working. The alternative explanation, however, is that the patients who made the best immune responses were the healthier patients with the better prognosis, and they would have survived longest in any event, even without the vaccine. In other words, the immune responses may simply be a simple reflection of a better health status, not an indication that the vaccine had any beneficial effects. As such, these immune 'false friends' may have tempted some to embark on expensive phase III trials without a solid rationale.

From Wikipedia, the free encyclopedia


  1. Anonymous said...

    I recently came across your blog and have been reading along. I thought I would leave my first comment. I don't know what to say except that I have enjoyed reading. Nice blog. I will keep visiting this blog very often.


  2. Josue said...

    Several years ago I attended a conference called soft cialis, in which to market a pickup, but I talk about this drug and others, I find it quite interesting to learn these things that we can build on many things besides the knowledge

  3. Dean said...

    greetings to all.
    I would first like to thank the writers of this blog by sharing information, a few years ago I read a book called Real Estate Investment costa rica in this book deal with questions like this one.

  4. niz said...

    Hello .. firstly I would like to send greetings to all readers. After this, I recognize the content so interesting about this article. For me personally I liked all the information. I would like to know of cases like this more often. In my personal experience I might mention a book called Generic Viagra in this book that I mentioned have very interesting topics, and also you have much to do with the main theme of this article.

  5. Chad said...

    Costa Rica is a country of beautiful landscapes, beaches and lush variety of plant and animal species. Visit

    In Costa Rica will always find a variety of animals and plants that beautify our landscape. Come and see the beauty of our land
    costa rica real estate

  6. Chad said...

    The people of Costa Rica is warm in his dealings, kind and hardworking. Visit our country and will enjoy the natural beauty of the find

    When you want to know a country full of beautiful natural landscapes come to Costa Rica, a place of beauty in every way, come and visit our land, you'll easily fall in love with Costa Rica
    costa rica investment